Carbonylations
The company has the capability to handle reactions involving carbon monoxide at a commercial scale.
Capacity to handle CO
Hyderabad |
Vizag |
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- Acylation : Handled AlCl3 and BCl3 on scale.
- Amination : Cu mediated amination in autoclave pressure.
- Amidation : Ammonia, methylamine, ethylamine and anilines on acid chlorides of alkyl and aryl acids.
- Condensation : Aldol, Claisen, Dieckmen, Mannich, Stobbe, Friedlander and Knovenagel.
- Grignards : Handled Turbo Grignards and Grignard reagents with lanthanum chloride and Lithium chloride complexes.
- Diazotisation : Handled Sodium nitrite, Isoamyl nitrite and Tert-butyl nitrite on scale.
- Dehalogenation : Dehalogenation reactions carried on aliphatic and aromatic compounds using metal insertion (Zn, Pd, Sn, Mg, etc).
- Hydrogenation : Debenzylations, Olefins, Nitro, Cyano and Oxime reductions
- Heterocyclic Chemistry : Synthesized Pyrazoles, Oxazoles, Isoxazoles, Thiazoles, Oxadiazoles, Pyrimidines, Pyrazines, Morpholines, Triazoles, Indoles,Quinolines Isoquinolines, Benzofurans, Imidazoles, Benzimidazoles.
- Reduction : LiAlH4, NaBH4, LiBH4, Dibal-H, Vitride, Triethylsilane, NaBH4/CeCl3 and NaBH4/BF3Etherate/TMSCl.
- Resolutions and separations
- Oxidation : Oxidations using Tempo, MCPBA, H2O2, Oxone and also palladium and RuCl2(PPh3)3 on scale.
- Suzuki Coupling : Using Pd/C, Pd(OAc)2, PdCl2(PPh3)2, Pd(PPh3)4, Pd(dppf)Cl2 in dry and aqueous conditions.
- Sonogashira Coupling : Synthesis of alkynes.
- Peptide Chemistry : Handled peptide coupling reagents – DCC EDCl, TBTU and HBTU. Synthesized tetra-peptide with 4 different amino acids.
