Site icon Avra Labs


Avra Lab is a leading Active Pharmaceutical Ingredients (API) manufacturer founded by a scientist renowned as one of the most distinguished ones in India. We focus on over 7 therapeutic areas and manufacture advanced API formulations with a commitment to quality. Our products cater to pharma companies all over the world with a record of over 25 years of excellence.

We are the Active Pharmaceutical Ingredients (API) suppliers of Lenalidomide, Misoprostol, Ticagrelor, Carfilzomib, Palbociclib, Eltrombopag Olamine, Macitentan, Pimavanserin and more.

API Products List

Therapeutic Area
Products Status
Anti-Cancer Irinotecan Hydrochloride USDMF No. 30516 / CEP (Pipeline)/ WHO GMP
Anti-Thrombotic Ticagrelor USDMF No. 033937 / WHO GMP
Ticagrelor, sold under the brand name Brilinta among others, is a medication used for the prevention of stroke, heart attack and other events in people with acute coronary syndrome, meaning problems with blood supply in the coronary arteries. The drug is produced by AstraZeneca. Avra provides complete GMP manufacturing of Ticagrelor and has a USDMF filed with number 033937
Anti-Cancer Lenalidomide Open part DMF/ WHO GMP
Lenalidomide is an Oncology drug sold under the trade name Revlimid and is a medication used to treat multiple myeloma and myelodysplastic syndromes among others. Lenalidomide was approved for medical use in the United States in 2005 and was launched by Celgene. It is on the World Health Organization’s List of Essential Medicines. Avra provides complete GMP manufacturing of Lenalidomide API for Form-A, Form-B and Form-I and has an Open Part DMF available.
Anti-Ulcer Misoprostol 1% dispersion in HPMC Tech Pack
Anti-Cancer Pazopanib Hydrochloride COA and samples (ODMF-Pipeline)
Anti-Cancer Carfilzomib COA and samples
Anti-Cancer Methotrexate COA and samples (ODMF-Pipeline)
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn’s disease. Avra provides complete GMP manufacturing of Methotrexate.
Anti-Cancer Topotecan Hydrochloride COA
Anti-Cancer Palbociclib R&D
Hematology Eltrombopag Olamine COA and samples (ODMF-Pipeline)
Eltrombopag is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). It was discovered as a result of research collaboration between GlaxoSmithKline and Ligand Pharmaceuticals. It is being manufactured and marketed by Novartis under the trade name Promacta in the US and is marketed as Revolade in the EU. Avra provides complete GMP manufacturing of Eltrombopag Olamine API.
PAH Macitentan R&D
Psoriatic Arthritis Apremilast R&D
Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. It may also be useful for other immune system related inflammatory diseases. Avra provides complete GMP manufacturing of Apremilast.
Antipsychotic Pimavanserin R&D
Name CAS No.
Irinotecan Intermediates
7-Ethyl-10-hydroxycamptothecin (SN-38) (USDMF No. 27429) 86639-52-3
SN-38 is an antineoplastic drug in the Oncology segment. It is the active metabolite of Irinotecan. Antibody-drug conjugates (ADCs) that exploit the active metabolite SN-38 have shown great promise in new cancer treatment technologies. Avra provides complete GMP manufacturing of fully synthetic SN-38 in a USFDA approved facility and has USDMF filed with number 27429
(S)-8-Ethyl-8-hydroxy-2,3,5,8-tetrahydro-6-oxa-3a-aza-cyclopenta [b]naphthalene-1,4,7-trione 110351-94-5
S-Trione is an intermediate of SN-38, which is an antineoplastic drug in the Oncology segment and the active metabolite of Irinotecan. Avra provides complete GMP manufacturing of fully synthetic S-Trione.
2’-Amino-5’-hydroxypropiophenone 35364-15-9
Topotecan Intermediate
10-Hydroxycamptothecin (USDMF No. 26025) 19685-09-07
Pazopanib HCl Intermediate
2,4-Dichloropyrimidine 3934-20-1
2,4-Dichloropyrimidine is used direclty as a human skin sensitizer. It is also used in the manufacturing of Pazopanib. Pazopanib, sold under the brand name Votrient, is an anti-cancer medication. It has been approved for renal cell carcinoma and soft tissue sarcoma by numerous regulatory administrations worldwide. Avra provides complete GMP manufacturing of 2,4-Dichloropyrimidine
5-Amino-2-methylbenzenesulfonamide 6973-09-7
Ticagrelor Intermediate
2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d](1,3)dioxol-4-yl)oxy)ethanol, 274693-26-4
Carfilzomib Intermediates
(S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenyipropanoic acid 868540-16-3
(S)-2-amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one trifluoroacetic acid salt 247068-85-5
Osimertinib Intermediates
4-Fluoro-2-methoxy-5-nitroaniline 1075705-01-9
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine 1421372-94-2
Dapagliflozin and Ertugliflozin Intermediates
(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone 461432-22-4
5-Bromo-2-chloro-4′-ethoxydiphenylmethane 461432-23-5
Eltrombopag Olamine
3′-amino-2′-hydroxy-1,1′-biphenyl-3-carboxylic acid 376592-93-7
2-Methoxy-3-nitrobiphenyl-3-carboxylic acid 376591-94-5
2-bromo-6-nitrophenol 13073-25-1
Camptothecin 7689-03-4
Camptothecin is an anti-cancer drug compund isolated from the bark and stem of the tree, Camptotheca acuminata. Avra holds a patented process and is the world’s largest producer for fully-synthetic manufacturing of Camptothecin derivates including Irinotecan, SN-38, S-Trione, AHP and Topotecan intermediates
7-Ethylcamptothecin 78287-27-1
Olivetol 500-66-3
Methyl olivetolate 58016-28-7
3-Oxocyclobutanecarboxylic acid 23761-23-1
6-Hydroxy-1,2,3,4-tetrahydroisoquinoline 14446-24-3
2-Amino-5-bromobenzaldehyde 29124-57-0
2,4-Dimethoxypyrimidine 3551-55-1
Quinoxaline-2-carboxaldehyde 1593-08-4
2-Chloro-1,3,2-dioxaphospholane 2-oxide 6609-64-9
3,4-benzyloxybenzaldehyde 5447-02-9
2-Ethylmorpholine 52769-10-5
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 286961-14-6
trans-1-Propenylboronic acid pinacol ester 83947-58-4
Trimethylsulfoxonium chloride 5034-06-0
Tri-tert-butylphosphoniumtetrafluoroborate 131274-22-1
2-phenylpyridine 1008-89-5
3-Hydroxyazetidine hydrochloride 18621-18-6
3-Bromopyridazine Hydrobromide —-
All transactions are carried out in conformity with patent laws applicable in the user country. Responsibility with respect to third party’s patent right in a specific country lies exclusively with the buyer. Products currently covered by valid US patents are offered for R&D use in accordance with 35 USC 271 A13(1)

Created By

Exit mobile version